Diabetes & Endocrinology News

 
 
  • Early Age at First Period Raises Type 2 Diabetes Risk In a study of US women under age 65, "extremely early" age at first menstrual period was associated with greater risk for type 2 diabetes and stroke compared with having menarche at age 13.
  • US Life Expectancy Still Lags: What Doctors Can Do Today Learn why American life expectancy has eroded and what you can do with patients to help fix the problem.
  • Link Between Vitamin D Deficiency and Obesity Unclear Debates about the association of vitamin D levels with obesity are ongoing, and confounding factors remain to be elucidated.
  • Next Up for PCPs: Managing CKM An AHA presidential advisory introduced the concept of cardiovascular-kidney-metabolic health, with PCPs as key providers.
  • How’s the Food? Rate Your Hospital Cafeteria Historically, hospital cafeterias have not been celebrated for the quality of their cuisine, typically feeding their staff from the same kitchen that prepared patient meals. How would you rate your hospital's cafeteria?
  • MDMA Therapy for Loneliness? Researchers Say It Could Work Studies show the drug can make people more social and less defensive, effects that some say could be harnessed to treat loneliness in therapy.
  • Eli Lilly's Obesity Drug Now Available in US Pharmacies Eli Lilly's recently approved obesity treatment is now available in US pharmacies and could cost customers whose health insurance does not cover the drug $550 a month, or half the list price, the company said on Tuesday.
  • Roche Joins Race for Obesity Drugs With $2.7 Billion Carmot Deal Roche agreed to take over unlisted obesity drug developer Carmot Therapeutics for $2.7 billion upfront, joining a list of contestants seeking to challenge the dominant makers of weight-loss drugs Novo Nordisk and Eli Lilly.
  • Reducing Albumin Improves Kidney and Heart Function The tablet drug finerenone significantly reduces kidney risk in people with type 2 diabetes and also protects heart health, researchers found.
  • Statin Use Remains Low for At-Risk Patients Expanded prescribing guidelines have not boosted statin use among patients who are at risk for atherosclerotic cardiovascular disease.
  • No Benefit of Levothyroxine in Heart Donors New data challenge the common practice of levothyroxine administration in potential heart donors after brain death to preserve heart function and make more hearts available for transplantation.
  • How Gender-Affirming Treatment Affects Erythrocytosis Gender-affirming hormone therapy has been associated with a risk for abnormal blood cell elevation, but a new study finds that it is a lower risk than was previously believed.
  • US Obesity Docs Expect Zepbound to Show Heart Benefit Some leading US obesity specialists say they expect Eli Lilly’s powerful weight-loss drug Zepbound will produce the same or similar heart benefits as Novo Nordisk’s popular Wegovy.
  • Launches of Novo Nordisk's Weight-Loss Drug Wegovy Novo Nordisk is pushing ahead with the launches of weight-loss drug Wegovy in Europe and Asia, even as it struggles to keep up with demand.
  • EU Watchdog Seeks More Safety Data From GLP-1 Drugmakers The EU's drug watchdog will request more data from makers of a class of diabetes and weight-loss drugs including Ozempic and Wegovy to further investigate suicidal thoughts in some patients taking them.
  • Pfizer Drops Twice-Daily Version of Obesity Pill Over Side Effects Pfizer said on Friday it would not advance a twice-daily version of oral weight-loss drug danuglipron into late-stage studies after most patients dropped out of its midstage trial with high rates of side effects such as nausea and vomiting.
  • Smoking Alters Salivary Microbiota Changes in oral microbiota caused by cigarette smoking could contribute to development of chronic health conditions.
  • Procedures May Ease Postmenopausal Pain Better Than Drugs Postmenopausal women report more significant improvements in chronic pain after procedural interventions when compared with their younger counterparts, despite being notably less likely to use muscle relaxants, TCAs, and benzodiazepines.
  • AI Aids Type 2 Diabetes Insulin Dosing A patient-facing voice-based conversational artificial intelligence application helped patients with type 2 diabetes optimize their insulin doses.
  • What Is the Dark Side of GLP-1 Receptor Agonists? Doctors who prescribe this class of medication should be aware of the rare side effects with which it is associated, said an obesity expert.
  • Novo Nordisk Finds Compounded Wegovy Up to 33% Impure Novo Nordisk on Thursday said it sued one compounding pharmacy and refiled a lawsuit against another after finding their products claiming to contain the active ingredient for its in-demand weight-loss drug were impure.
  • Late-Life Increases in Pulmonary Pressure, Hypertension Age-related increases in pulmonary artery systolic pressure occur in concert with worsening left ventricular diastolic dysfunction and contribute to late-life dyspnea, new data show.
  • ACG 2023 Low-Dose Aspirin: No Flares in Pregnant Patients With IBD Low-dose aspirin is recommended for pregnant women who are at risk of hypertensive disorders, such as eclampsia, preeclampsia, and gestational diabetes.
  • DMARDs Linked to Reduced Thyroid Disease Incidence In a large Swedish rheumatoid arthritis cohort, the incidence of thyroid disease declines after RA diagnosis vs the general population, with the effect strongest among those treated with anti-rheumatic drugs.
  • Insufficient Sleep Impairs Women's Insulin Sensitivity Restricted sleep of around 6 hours per night may be enough of a reduction to increase the risk for impaired insulin sensitivity in women, particularly if they are postmenopausal, suggests a US trial.
  • More Weight Loss With Mounjaro Than Ozempic: Data Analysis Overweight or obese adults lost more weight and shed pounds faster using Eli Lilly's Mounjaro than those taking Novo Nordisk's popular rival weight loss drug.
  • AANEM 2023 Novel Myasthenia Gravis Therapies Bring Opportunities New treatments for myasthenia gravis are bringing new promise to patients, but their use must be balanced against short-term and long-term risks.
  • Despite Effective Therapies, Fibroid Care Still Lacking Minimally invasive procedures for uterine fibroids are highly effective, but gaps in diagnosis, racial disparities, and lack of availability outside urban academic centers limit their use.
  • Novo to Launch Wegovy in Asia With February Roll-Out in Japan Novo Nordisk will launch its hugely popular anti-obesity drug in Japan on February 22, its first launch in Asia, even as it struggles to keep up with demand in existing markets.
  • Urine Test Identifies Endocrine Hypertension With Help From AI The test uses machine learning to assess the likelihood that a person’s hypertension is secondary to cortisol and aldosterone excess.
  • Should Physicians Go to Work When Sick? Although most doctors believe it's best to stay home if they're ill, today's healthcare system makes the answer much more complicated.
  • Even an Hour's Walk a Week Lowers Risk in Type 2 Diabetes Leisure time activity equivalent to less than 1.5 hours' walking time per week may be enough to substantially reduce the risk for neuropathy and nephropathy in type 2 diabetes, say Danish researchers.
  • Both Too Much and Not Enough Sleep Raises T2D Risk Sleeping 3 or more hours over or under the average sleep duration of 8 hours increases the risk for type 2 diabetes, regardless of other factors, indicates Dutch study analysis.
  • Apple Cider Vinegar, Fenugreek Best Herbal Remedies for T2D A new analysis found some herbal remedies including apple cider vinegar and fenugreek seeds are better than others at helping to manage type 2 diabetes.
  • Jury Still Out on Stopping GLP-1 RAs Prior to Endoscopy Five professional gastroenterology organizations caution that more data are needed to understand if and when GLP-1 receptor agonists should be held prior to elective endoscopy.
  • UK's First Living Donor Uterus Transplant a Success After 25 years' preclinical research, a British surgical team reported the UK's first living donor uterus transplant, with both donor and recipient doing well 10 weeks post-operatively.
  • As MOC Debate Heats Up, Cardiology Societies Weigh In The MOC process is once again under attack by cardiologists and other specialty physicians. A petition aiming to end the requirements has garnered more than 17,000 and counting signatures.
  • Artificial Sweeteners Increase Cardiovascular Risk A recent scientific review confirms that artificial sweeteners affect primary cardiovascular risk factors.
  • Firefighters Fight Fat With Mediterranean Diet Adoption A communal approach to adopting the Mediterranean diet lowered firefighters' risks for cardiovascular disease and cancer and improved their dietary adherence, both at home and work.
  • A1c Not Linked to Postop Complications in Kids With Diabetes Findings suggest no need to delay elective surgery in order to optimize glycemic control in children with type 1 or type 2 diabetes.